CASE STUDY Skin hydration Measuring the effect of mineral oil-based moisturizers on skin barrier function

BENEFITS
 of the DermaLab Combo
 Comprehensive measurements:  
In the case study the DermaLab Combo 
provided a dual approach by accurately  
measuring both skin hydration and  
transepidermal water loss (TEWL), 
which was essential for evaluating the 
performance of different moisturizers.
 Reliable and consistent data: 
The device ensured the collection of 
consistent and precise data throughout 
the study, allowing for a robust assess
ment of each product’s impact on skin 
barrier function.
 Versatility: 
By combining hydration and TEWL 
measurements, the DermaLab Combo 
offers a complete view of the skin’s  
barrier function. This versatility makes 
it an invaluable tool for both dermato
logical research and cosmetic efficacy 
studies

CASE STUDY Skin hydration Measuring the effect of mineral oil-based moisturizers on skin barrier function

Case information 
Study: ”Investigating the Impact of Mineral Oil-Based Moisturizers on Skin Barrier  
Function”, published in Asian Journal of Pharmacy and Pharmacology.
 This study aimed to evaluate the effect of mineral oil in various moisturizers on normal 
skin’s barrier function, focusing on hydration and transepidermal water loss (TEWL).
 Solution and method
 The study involved 15 female volunteers, 
aged 20-25, who were divided into three 
groups, each using a different brand 
of mineral oil-based moisturizer. Each  
volunteer applied the assigned moistu
rizer to one volar forearm twice daily for 
3 weeks, while the other forearm served 
as an untreated control.
 Measurements of TEWL and skin hydra
tion were taken before the study began, 
and after 3 weeks, using the DermaLab 
Combo device. This device ensures  
precise and reliable assessments by 
measuring both TEWL and skin hydration.
 Results and conclusions 
By use of the Hydration Pin Probe the 
study found that all tested moisturizers 
increased skin hydration, despite a rise 
in TEWL. The study concluded that  
while mineral oil-based moisturizers did 
not reduce TEWL as expected, they 
were effective in improving skin hydration.

 Read the Full Article:  
https://ajpp.in/uploaded/p27.pdf